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CMV Serology Test

By Ashley | February 5, 2010

The CMV Serology test is done to determine whether antibodies to the cytomegalovirus (CMV) are present in the blood. The test is able to detect a current or a past CMV infection, and is usually recommended for people who are at risk, especially those with a suppressed immune system, and those who are recipients of organ transplants. The test is sometimes also done in newborns to detect if a CMV infection has been passed on by the mother.

Serology tests study the serum in the body to detect any antibody contents.

Diseases which can be detected by a CMV test:

  • Syphilis
  • Human immunodeficiency virus (HIV)
  • Viral hepatitis
  • Amebic liver abscess
  • Rubella
  • Measles
  • Anthrax
  • Amebiasis
  • Meningitis
  • Fungal arthritis
  • Viral arthritis
  • Brucellosis
  • Tularemia

Procedure to Conduct a CMV Serology Test

In this a sample of blood, which will be tested, is drawn from a vein.

  • The person who will draw the blood uses an antiseptic to first clean the site from where blood will be drawn. This is usually on the back of the hand or inside the elbow.
  • An elastic band may be wrapped around the upper arm to help the blood to swell in the vein.
  • A needle is now inserted and blood is collected from the vein, and stored in a tube or airtight vial.
  • The elastic band and needle are removed.
  • The puncture site is covered with a bandage to prevent further bleeding.
  • In babies and children, a lancet may be used to pierce the skin.

Preparation Required

There is not much preparation needed.

  • But speak to your doctor in case you are on any medication which may interfere with the results of the test.
  • If you are on any blood thinning medicines, you may be asked to stop that for a day or two prior to the test.

Conditions During CMV Serology Test

  • You may feel a slight pricking or a stinging sensation, or a little pain when the needle goes in.
  • Later, you might have a slight throbbing at the puncture for a day or two.

Risks Involved

There is not much risk involved in the test, except for a few minor ones.

  • You may have excessive bleeding from the puncture site.
  • Blood may accumulate under the skin, at the puncture site, causing hematoma.
  • You may feel light-headed or faint after the blood is drawn.
  • There is always a slight risk of infection, whenever the skin is broken.